Triosephosphate isomerase (TPI) deficiency is an autosomal recessive disorder caused by various mutations in the gene encoding the key glycolytic enzyme TPI. A drastic decrease in TPI activity and an increased level of its substrate. dihydroxyacetone phosphate. have been measured in unpurified cell extracts of affected individuals. http://www.gymnaziastore.com/product-category/lubricantes-aceites-de-masaje-gels/